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Afrezza® inhaled insulin

Afrezza® is the only ultra rapid-acting inhaled insulin that starts lowering blood sugars in ~12 minutes for adults living with type 1 or type 2 diabetes.

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I use Afrezza® inhaled insulin for all my meals and snacks. In my experience, it’s had an impact on my A1C, and helps keep me within my target range.
Brec Bassinger,
Afrezza User

Brec is a Paid Spokesperson for MannKind. Results may vary.

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TAKE CONTROL WITH AFREZZA®

Afrezza®, the only ultra rapid-acting inhaled insulin, delivers glucose management in the
moment for adults living with type 1 or type 2 diabetes.

DISCOVER MANAGEMENT
IN THE MOMENT WITH AFREZZA®

Learn more about Afrezza®, the only ultra rapid-acting inhaled insulin.

no-planning

NO
PLANNING

Afrezza® lets you inhale your insulin right when food arrives — even unexpectedly — so you can be spontaneous but still in control.

no-waiting

NO
WAITING

Afrezza® lowers your blood sugar fast*,  similar to the body’s natural insulin response.

*Starts lowering blood sugars in ~12 minutes.

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NO
NEEDLESTICKS

Afrezza® lowers your blood sugar at mealtime without the need for mealtime injections.

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CONTROL YOU
CAN COUNT ON

Afrezza® has proven mealtime control in studies of more than 3,000 people with either type 1 or type 2 diabetes.

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TALK TO A DOCTOR

Find out if Afrezza® is right for you.

UpScript*, a telemedicine platform, lets you speak with a healthcare provider to see if Afrezza® is right for you, all from the comfort of your own home.

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Find a healthcare provider near you that has experience prescribing Afrezza®.**

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PAYING FOR AFREZZA®

Did you know that most patients do not pay the list price for Afrezza®?
With the Afrezza® Savings Card, eligible commercially insured patients may pay as little as $35 per month.***

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GET PRACTICAL HOW-TOS

Learn what to expect when taking Afrezza®, how to store it, and more.

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IMPROVE YOUR EXPERIENCE

Whether you are new to Afrezza® or just want to learn more, our Patient Support Guides are here to provide personalized support through every step of the Afrezza® journey.

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YOUR QUESTIONS, ANSWERED

Learn more about Afrezza® in our FAQs.

* Third-party website; does not constitute an endorsement or recommendation by MannKind Corporation.

** The physician locator tool is provided by MannKind Corp. (“MannKind”) solely to assist you in locating a physician who has experience with Afrezza®. This physician locator tool should not be construed in any way as an endorsement or recommendation by MannKind as to the qualifications of any physicians listed in this tool or the quality of medical care they can provide. MannKind makes no guarantees that using a physician from this list will result in your desired outcome. It is wholly and solely your responsibility to assess the qualifications of a potential physician. MannKind recommends that you meet and discuss the benefits and risks of treatments and the procedure to administer the product with the potential physician.

***  What you pay for Afrezza® will depend on your insurance plan. Each plan has different preferred drug lists and out-of-pocket amounts, and most include an annual deductible. If you haven’t met your deductible, you’ll see higher prices until the deductible is met, then your out-of-pocket cost will likely drop. This offer is available for patients with commercial drug insurance coverage. It is not valid for patients enrolled in Medicare, Medicaid, or other federal or state healthcare programs. Maximum savings limit applies; patient out-of-pocket expense may vary. If the patient’s health plan does not cover Afrezza® or requires a prior authorization, contact AfrezzaAssist℠ for more information. If approved by the patient’s health plan to take Afrezza®, a patient will pay as little as $35 per month. This applies to patient out-of-pocket costs, including deductible, co-insurance, and copayments for Afrezza®. See full Program Terms, Conditions, and Eligibility Criteria.

References:

  1. Afrezza® (insulin human) Inhalation Powder Prescribing Information. MannKind Corporation.

US-AFR-2399

Read more

What is AFREZZA?

Read more

Important Safety Information

What is the most important information I should know about AFREZZA? AFREZZA can cause serious side effects, including:

Sudden lung problems (bronchospasms). In a study, some AFREZZA-treated patients with asthma, whose asthma medication was temporarily withheld, experienced sudden lung problems. Do not use AFREZZA if you have long-term (chronic) lung problems such as asthma or chronic obstructive pulmonary disease (COPD). Before starting AFREZZA, your healthcare provider will give you a breathing test to check how your lungs are working.

 

Important Safety Information(cont’d)

Who should not use Afrezza®?

Do not use Afrezza® if you:

  • Have chronic lung problems such as asthma or COPD.
  • Are allergic to regular human insulin or any of the ingredients in Afrezza®.
  • Are having an episode of low blood sugar (hypoglycemia).

What should I tell my healthcare provider before using Afrezza®?

Before using Afrezza®, tell your healthcare provider about all your medical conditions, including if you:

  • Have lung problems such as asthma or COPD
  • Have or have had lung cancer
  • Are using any inhaled medications
  • Smoke or have recently stopped smoking
  • Have kidney or liver problems
  • Are pregnant, planning to become pregnant, or are breastfeeding. Afrezza® may harm your unborn or breastfeeding baby.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins or herbal supplements.

Before you start using Afrezza®, talk to your healthcare provider about low blood sugar and how to manage it.

What should I avoid while using Afrezza®?

While using Afrezza® do not:

  • Drive or operate heavy machinery, until you know how Afrezza® affects you.
  • Drink alcohol or use over-the-counter medicines that contain alcohol.
  • Smoke.

What are the possible side effects of Afrezza®?

Afrezza® may cause serious side effects that can lead to death, including:

See “What is the most important information I should know about Afrezza®?”

  • Low blood sugar (hypoglycemia). Signs and symptoms that may indicate low blood sugar include:
    • Dizziness or light-headedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability or mood change, hunger.
  • Decreased lung function. Your healthcare provider should check how your lungs are working before you start using AFREZZA, 6 months after you start using it, and yearly after that.
  • Lung cancer. In studies of Afrezza® in people with diabetes, lung cancer occurred in a few more people who were taking Afrezza® than in people who were taking other diabetes medications. There were too few cases to know if lung cancer was related to Afrezza®. If you have lung cancer, you and your healthcare provider should decide if you should use Afrezza®.
  • Diabetic ketoacidosis. Talk to your healthcare provider if you have an illness. Your Afrezza® dose or how often you check your blood sugar may need to be changed.
  • Severe allergic reaction (whole body reaction). Get medical help right away if you have any of these signs or symptoms of a severe allergic reaction:
    • A rash over your whole body, trouble breathing, a fast heartbeat, or sweating.
  • Low potassium in your blood (hypokalemia).
  • Heart failure. Taking certain diabetes pills called thiazolidinediones or “TZDs” with Afrezza® may cause heart failure in some people. This can happen even if you have never had heart failure or heart problems before. If you already have heart failure it may get worse while you take TZDs with Afrezza®. Your healthcare provider should monitor you closely while you are taking TZDs with Afrezza®. Tell your healthcare provider if you have any new or worse symptoms of heart failure including:
    • Shortness of breath, swelling of your ankles or feet, sudden weight gain.

Treatment with TZDs and Afrezza® may need to be changed or stopped by your healthcare provider if you have new or worse heart failure.

Get emergency medical help if you have:

• Trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, confusion.

The most common side effects of Afrezza® include:

  • Low blood sugar (hypoglycemia), cough, sore throat

These are not all the possible side effects of Afrezza®. Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088 (1-800-332-1088).

Please See Full Prescribing Information, including BOXED WARNING, Medication Guide and Instructions for Use for AFREZZA.


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